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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Terf1
telomeric repeat binding factor 1
MGI:109634
31 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Terf1tm1.1Blas/Terf1tm1.1Blas
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal chromosome morphology J:152077
abnormal telomere length J:152077
decreased cell proliferation J:152077
early cellular replicative senescence J:152077
Terf1tm1.1Blas/Terf1tm1.1Blas
Tg(KRT5-cre)1Tak/0
involves: 129 * C3H * C57BL/6 * SJL
abnormal chromosome morphology J:152077
abnormal esophageal epithelium morphology J:152077
abnormal esophagus morphology J:152077
abnormal filiform papillae morphology J:152077
abnormal keratinocyte physiology J:152077
abnormal palate morphology J:152077
abnormal skin development J:152077
abnormal skin morphology J:152077
abnormal skin physiology J:152077
abnormal stomach epithelium morphology J:152077
abnormal telomere length J:152077
abnormal tongue epithelium morphology J:152077
absent hair follicles J:152077
absent sebaceous gland J:152077
decreased body weight J:152077
epidermal hyperplasia J:152077
hyperkeratosis J:152077
impaired skin barrier function J:152077
increased skin pigmentation J:152077
orthokeratosis J:152077
perinatal lethality, incomplete penetrance J:152077
postnatal growth retardation J:152077
skin inflammation J:152077
Terf1tm1Tdl/Terf1+
involves: 129S2/SvPas
no abnormal phenotype detected J:85440
Terf1tm1Tdl/Terf1tm1Tdl
involves: 129S2/SvPas
abnormal ectoplacental cone morphology J:85440
abnormal extraembryonic tissue morphology J:85440
abnormal inner cell mass apoptosis J:85440
absent inner cell mass proliferation J:85440
embryonic lethality between implantation and somite formation, complete penetrance J:85440
Terf1tm2.1Tdl/Terf1tm2.1Tdl
involves: 129P2/OlaHsd * C57BL/6
early cellular replicative senescence J:157331

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory