Sftpa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sftpa1
surfactant associated protein A1
MGI:109518

15 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sftpa1^tm1Haw/Sftpa1^tm1Haw involves: 129/Sv * C57BL/6 * CD-1	abnormal cytokine level	J:86024
	abnormal inflammatory response	J:85432
	abnormal interferon level	J:86024
	abnormal interleukin level	J:86024
	abnormal pulmonary alveolar parenchyma morphology	J:86024
	abnormal respiratory system physiology	J:86024
	abnormal surfactant physiology	J:86024
	increased lung compliance	J:85432
	increased susceptibility to Orthomyxoviridae infection	J:86024
Sftpa1^tm1Kor/Sftpa1^tm1Kor B6.129P2-Sftpa1^tm1Kor	abnormal phospholipid level	J:130520
Sftpa1^tm1Kor/Sftpa1^tm1Kor B6.129P2-Sftpa1^tm1Kor	abnormal surfactant physiology	J:130520
Sftpa1^tm1Kor/Sftpa1^tm1Kor involves: 129P2/OlaHsd	abnormal phospholipid level	J:107841
	abnormal surfactant physiology	J:107841
	normal immune system phenotype	J:130958
	lung inflammation	J:107841
Sftpa1^tm1Kor/Sftpa1^tm1Kor involves: 129P2/OlaHsd * Black Swiss * C3H/HeN	increased susceptibility to bacterial infection	J:130297
	postnatal lethality, complete penetrance	J:130297
Sftpa1^tm1Kor/Sftpa1^tm1Kor involves: 129P2/OlaHsd * NIH Black Swiss	abnormal surfactant physiology	J:111449
	normal immune system phenotype	J:35250
	increased susceptibility to bacterial infection	J:110382, J:120552
	lung inflammation	J:110382
	normal respiratory system phenotype	J:35250

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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