Sftpb Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sftpb
surfactant associated protein B
MGI:109516

16 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sftpb^tm1Jaw/Sftpb⁺ involves: 129S2/SvPas	abnormal surfactant secretion	J:59460
	decreased lung compliance	J:59460
	decreased total lung capacity	J:59460
	increased susceptibility to injury	J:59460
Sftpb^tm1Jaw/Sftpb^tm1Jaw involves: 129S2/SvPas * Black Swiss	abnormal lipid homeostasis	J:28289
	abnormal pulmonary alveolus morphology	J:28289
	abnormal surfactant composition	J:28289
	abnormal surfactant physiology	J:28289
	abnormal surfactant secretion	J:28289
	abnormal type II pneumocyte morphology	J:28289
	absent alveolar lamellar bodies	J:28289
	atelectasis	J:28289
	cyanosis	J:28289
	neonatal lethality, incomplete penetrance	J:28289
	pup cannibalization	J:28289
	respiratory distress	J:28289
	respiratory failure	J:28289

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23