Nup98 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nup98
nucleoporin 98
MGI:109404

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nup98^em1(IMPC)Bay/Nup98^em1(IMPC)Bay C57BL/6N-Nup98^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
Nup98^tm1Bmaf/Nup98⁺ involves: 129S6/SvEvTac * C57BL/6	abnormal level of surface class I molecules	J:110907
	abnormal level of surface class II molecules	J:110907
	abnormal MHC II cell surface expression on macrophages	J:110907
	decreased B cell number	J:110907
	decreased CD4-positive, alpha-beta T cell number	J:110907
	decreased IgG1 level	J:110907
	decreased IgG level	J:110907
	decreased T cell proliferation	J:110907
	increased T cell proliferation	J:110907
Nup98^tm1Jvd/Nup98^tm1Jvd Not Specified	abnormal embryo development	J:125571
	abnormal gastrulation	J:125571
	decreased embryo size	J:125571
	perinatal lethality, complete penetrance	J:125571

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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