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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stx1a
syntaxin 1A (brain)
MGI:109355
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Stx1atm1Gwz/Stx1atm1Gwz
Not Specified 		normal behavior/neurological phenotype J:141037
decreased body weight J:141037
decreased fetal size J:141037
embryonic growth retardation J:141037
lethality at weaning, incomplete penetrance J:141037
lethality throughout fetal growth and development, incomplete penetrance J:141037
Stx1atm1Tfuj/Stx1atm1Tfuj
Stx1btm1Tmis/Stx1btm1Tmis
involves: C57BL/6J 		abnormal inhibitory postsynaptic currents J:214474
abnormal miniature excitatory postsynaptic currents J:214474
abnormal miniature inhibitory postsynaptic currents J:214474
abnormal synapse morphology J:214474
decreased excitatory postsynaptic current amplitude J:214474
decreased miniature inhibitory postsynaptic current amplitude J:214474
decreased miniature inhibitory postsynaptic current frequency J:214474
embryonic lethality, complete penetrance J:214474
Stx1atm2.1Sud/Stx1atm2.1Sud
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal mortality/aging J:138035
Stx1atm2.1Sud/Stx1atm2.1Sud
Stx1btm1.1Sud/Stx1btm1.1Sud
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal neuron morphology J:138035
abnormal synaptic vesicle recycling J:138035
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory