Stx1a Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stx1a
syntaxin 1A (brain)
MGI:109355

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Stx1a^tm1Tfuj/Stx1a^tm1Tfuj Stx1b^tm1Tmis/Stx1b^tm1Tmis involves: C57BL/6J	abnormal inhibitory postsynaptic currents	J:214474
	abnormal miniature excitatory postsynaptic currents	J:214474
	abnormal miniature inhibitory postsynaptic currents	J:214474
	abnormal synapse morphology	J:214474
	decreased excitatory postsynaptic current amplitude	J:214474
	decreased miniature inhibitory postsynaptic current amplitude	J:214474
	decreased miniature inhibitory postsynaptic current frequency	J:214474
	embryonic lethality, complete penetrance	J:214474
Stx1a^tm2.1Sud/Stx1a^tm2.1Sud Stx1b^tm1.1Sud/Stx1b^tm1.1Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal neuron morphology	J:138035
	abnormal synaptic vesicle recycling	J:138035

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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