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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lum
lumican
MGI:109347
33 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lumtm1.1(KOMP)Vlcg/Lum+
C57BL/6N-Lumtm1.1(KOMP)Vlcg/Ucd
increased circulating alanine transaminase level J:211773
increased circulating aspartate transaminase level J:211773
Lumtm1.1(KOMP)Vlcg/Lumtm1.1(KOMP)Vlcg
C57BL/6N-Lumtm1.1(KOMP)Vlcg/Ucd
abnormal tail morphology J:211773
preweaning lethality, complete penetrance J:211773
Lumtm1Chak/Lumtm1Chak
involves: 129S/Sv * CD-1
abnormal apoptosis J:89489
abnormal cornea morphology J:48068, J:70246
abnormal cornea posterior stroma morphology J:64730
abnormal corneal stroma development J:48068, J:81616
abnormal corneal stroma morphology J:48068, J:64730
abnormal dermal layer morphology J:48068
abnormal tendon morphology J:65867
bruising J:48068
normal cardiovascular system phenotype J:48068
corneal opacity J:48068, J:64730
decreased body size J:48068
decreased body weight J:48068
decreased corneal stroma thickness J:64730, J:81616
decreased fibroblast apoptosis J:89489
decreased skin tensile strength J:48068
normal digestive/alimentary phenotype J:48068
increased corneal light-scattering J:64730, J:81616
increased fibroblast proliferation J:89489
loose skin J:48068
sclera thinning J:83544
skin lesions J:48068
Lumtm1Wwk/Lumtm1Wwk
involves: 129P2/OlaHsd
abnormal inflammatory response J:128992
corneal opacity J:128992
decreased cornea thickness J:128992
decreased neutrophil cell number J:128992
Lumtm1Wwk/Lumtm1Wwk
involves: 129P2/OlaHsd * C57BL/6J
abnormal coat appearance J:60203
abnormal cornea posterior stroma morphology J:60203
abnormal corneal wound healing J:60203
abnormal skin condition J:60203
corneal opacity J:60203
delayed wound healing J:60203
reduced male fertility J:60203

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory