About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tradd
TNFRSF1A-associated via death domain
MGI:109200
14 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Traddtm1.1Mak/Tradd+
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N) 		decreased acute inflammation J:138824
Traddtm1.1Mak/Traddtm1.1Mak
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N) 		abnormal spleen follicular dendritic cell network J:138824
absent spleen germinal center J:138824
decreased acute inflammation J:138824
decreased circulating interleukin-6 level J:138824
decreased inflammatory response J:138824
decreased interleukin-6 secretion J:138824
decreased sensitivity to induced cell death J:138824
Traddtm1.1Mpa/Traddtm1.1Mpa
involves: BALB/cJ * C57BL/6 		abnormal interleukin level J:139030
abnormal spleen germinal center morphology J:139030
decreased circulating tumor necrosis factor level J:139030
decreased IgG level J:139030
decreased physiological sensitivity to xenobiotic J:139030
increased susceptibility to bacterial infection J:139030
Traddtm1.1Mpa/Traddtm1.1Mpa
involves: C57BL/6 		decreased interferon-beta secretion J:136289
Traddtm1.1Zgl/Traddtm1.1Zgl
involves: C57BL/6 * FVB/N 		decreased physiological sensitivity to xenobiotic J:139031
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory