Timp4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Timp4
tissue inhibitor of metalloproteinase 4
MGI:109125

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Timp4^em1(IMPC)Mbp/Timp4^em1(IMPC)Mbp C57BL/6N-Timp4^em1(IMPC)Mbp/MbpMmucd	abnormal heart morphology	J:211773
	abnormal skin morphology	J:211773
	absent optic nerve	J:211773
	increased freezing behavior	J:211773
	increased startle reflex	J:211773
	small heart	J:211773
	small spleen	J:211773
Timp4^tm1Lex/Timp4^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	normal cardiovascular system phenotype	J:211441
Timp4^tm1Vuo/Timp4^tm1Vuo involves: 129S7/SvEvBrd * C57BL/6	abnormal heart right ventricle morphology	J:165901
	abnormal myocardial fiber physiology	J:165901
	abnormal response to cardiac infarction	J:165901
	decreased coronary flow rate	J:165901
	increased heart left ventricle weight	J:165901
	increased susceptibility to induced morbidity/mortality	J:165901

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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