Fzd6 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fzd6
frizzled class receptor 6
MGI:108474

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Astn2^ridge/Astn2^ridge Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129 * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA	abnormal hair follicle orientation	J:228899
	abnormal hair texture	J:228899
Astn2^tm1.2Nat/Astn2^tm1.2Nat Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129 * 129S6/SvEvTac * BALB/cJ * C57BL/6 * CBA	abnormal hair follicle orientation	J:228899
	abnormal hair texture	J:228899
Fzd3^tm1Nat/Fzd3⁺ Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	oligozoospermia	J:105752
	reduced male fertility	J:105752
Fzd3^tm1Nat/Fzd3^tm1Nat Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlea morphology	J:105752
	abnormal cochlear outer hair cell morphology	J:105752
	abnormal crista ampullaris morphology	J:105752
	abnormal orientation of inner hair cell stereociliary bundles	J:105752
	abnormal tectorial membrane morphology	J:105752
	curly tail	J:105752
	eyelids open at birth	J:105752
	normal hearing/vestibular/ear phenotype	J:105752
	neonatal lethality, complete penetrance	J:105752
	open neural tube	J:105752

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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