Scn10a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scn10a
sodium channel, voltage-gated, type X, alpha
MGI:108029

19 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scn10a^Psm/Scn10a⁺ (C3H/HeN x C57BL/6J)F1	catalepsy	J:180381
Scn10a^Psm/Scn10a⁺ C57BL/6J-Scn10a^Psm	abnormal posture	J:180381
	abnormal tail movements	J:180381
	apnea	J:180381
	normal behavior/neurological phenotype	J:180381
	catalepsy	J:180381
	impaired righting response	J:180381
Scn10a^Psm/Scn10a⁺ involves: C3H/HeN * C57BL/6J	catalepsy	J:180381
Scn10a^Psm/Scn10a^Psm C57BL/6J-Scn10a^Psm	abnormal brain wave pattern	J:180381
	abnormal nervous system electrophysiology	J:180381
	abnormal posture	J:180381
	abnormal RR interval	J:180381
	abnormal single cell response	J:180381
	abnormal tail movements	J:180381
	apnea	J:180381
	normal behavior/neurological phenotype	J:180381
	catalepsy	J:180381
	decreased thermal nociceptive threshold	J:180381
	impaired righting response	J:180381
	sinus bradycardia	J:180381
Scn10a^tm1Jwo/Scn10a^tm1Jwo B6.129P2-Scn10a^tm1Jwo	abnormal mechanical nociception	J:76456
	abnormal thermal nociception	J:76456
	hypoalgesia	J:76456
Scn10a^tm1Lex/Scn10a^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal action potential	J:157066
	abnormal pain threshold	J:157013
	hyperalgesia	J:157013
	impaired ability to fire action potentials	J:157066

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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