Plxna2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plxna2
plexin A2
MGI:107684

13 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chat^tm2(cre)Lowl/Chat⁺ Plxna2^{tm1a(EUCOMM)Wtsi}/Plxna2^tm1Hfu involves: 129S6/SvEvTac * C57BL/6N * CBA/JNCrlj	abnormal amacrine cell morphology	J:202884
	abnormal dendrite morphology	J:202884
	abnormal retina inner plexiform layer morphology	J:202884
Plxna2^nmf454/Plxna2^nmf454 involves: C57BL/6J	abnormal cerebellar molecular layer	J:135408
	abnormal neuronal migration	J:135408
	ataxia	J:135408
	decreased body size	J:135408
	ectopic cerebellar granule cells	J:135408
Plxna2^{tm1a(EUCOMM)Wtsi}/Plxna2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Plxna2^{tm1a(EUCOMM)Wtsi}/Wtsi	increased mean corpuscular hemoglobin	J:211773
Plxna2^tm1Hfu/Plxna2^tm1Hfu B6.Cg-Plxna2^tm1Hfu	abnormal hippocampal mossy fiber morphology	J:135421
Plxna2^tm1Hfu/Plxna2^tm1Hfu involves: C57BL/6 * CBA	abnormal hippocampal mossy fiber morphology	J:160509
	abnormal neuronal migration	J:135408
	ectopic cerebellar granule cells	J:135408
	normal vision/eye phenotype	J:172268
Plxna2^tm1Hfu/Plxna2^tm1Hfu involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal amacrine cell morphology	J:202884
	abnormal dendrite morphology	J:202884
	abnormal lymphatic vessel morphology	J:226501
	abnormal neuron physiology	J:202884
	abnormal retina inner plexiform layer morphology	J:202884

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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