Irgm1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irgm1
immunity-related GTPase family M member 1
MGI:107567

2 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Igtp^em1Myam/Igtp^em1Myam Irgm1^em1Myam/Irgm1^em1Myam C57BL/6-Irgm1^em1Myam Igtp^em1Myam	increased susceptibility to parasitic infection	J:308470
Igtp^em1Myam/Igtp^em1Myam Irgm1^em1Myam/Irgm1^em1Myam Irgm2^em2Myam/Irgm2^em2Myam C57BL/6-Irgm1^em1Myam Igtp^em1Myam Irgm2^em2Myam	increased susceptibility to parasitic infection	J:308470
Irgm1^tm1Gat/Irgm1^tm1Gat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal immune system phenotype	J:87535
	increased circulating interferon-gamma level	J:87535
	increased circulating interleukin-12 level	J:87535
	increased susceptibility to bacterial infection	J:87535
	increased susceptibility to parasitic infection	J:87535

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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