Pex2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pex2
peroxisomal biogenesis factor 2
MGI:107486

41 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pex2^tm1Plf/Pex2^tm1Plf involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal adrenal cortex morphology	J:44975
	abnormal brain white matter morphology	J:44975
	abnormal circulating free fatty acids level	J:44975
	abnormal frontal bone morphology	J:44975
	abnormal head movements	J:44975
	abnormal interparietal bone morphology	J:44975
	abnormal liver morphology	J:44975
	abnormal motor capabilities/coordination/movement	J:44975
	abnormal neurocranium morphology	J:44975
	abnormal stratification in cerebral cortex	J:44975
	aphagia	J:44975
	normal behavior/neurological phenotype	J:44975
	decreased bone mineral density	J:44975
	decreased bone mineralization	J:44975
	decreased circulating cholesterol level	J:87591
	decreased embryo weight	J:44975
	decreased locomotor activity	J:44975
	delayed intramembranous bone ossification	J:44975
	impaired balance	J:44975
	neonatal lethality, incomplete penetrance	J:44975
	postnatal lethality, complete penetrance	J:44975
	trunk curl	J:44975
Pex2^tm1Plf/Pex2^tm1Plf involves: 129S1/Sv * 129X1/SvJ * Swiss Webster	abnormal bile composition	J:87591
	abnormal cerebellar foliation	J:83644
	abnormal cerebellar granule layer morphology	J:83644
	abnormal cerebellum external granule cell layer morphology	J:83644
	abnormal cerebellum morphology	J:83644
	abnormal gait	J:83644
	abnormal kidney physiology	J:83644
	abnormal liver morphology	J:83644
	abnormal liver physiology	J:87591
	abnormal motor capabilities/coordination/movement	J:83644
	abnormal Purkinje cell morphology	J:83644
	cholestasis	J:83644
	decreased brain size	J:83644
	decreased cholesterol level	J:87591
	decreased circulating cholesterol level	J:87591
	decreased circulating HDL cholesterol level	J:87591
	decreased liver cholesterol level	J:87591
	hepatic steatosis	J:83644
	impaired balance	J:83644
	limb grasping	J:83644
	microcephaly	J:83644
	postnatal growth retardation	J:83644
	postnatal lethality, complete penetrance	J:83644
	small cerebellum	J:83644

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23