Hmx2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hmx2
H6 homeobox 2
MGI:107159

30 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hmx2^{tm1.1(KOMP)Vlcg}/Hmx2^{tm1.1(KOMP)Vlcg} C57BL/6N-Hmx2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal auditory brainstem response	J:211773
	abnormal kidney morphology	J:211773
	enlarged kidney	J:211773
	increased bone mineral content	J:211773
	increased kidney weight	J:211773
	polycystic kidney	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Hmx2^tm1Tlu/Hmx2^tm1Tlu involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal crista ampullaris morphology	J:73069
	abnormal ear development	J:73069
	abnormal inner ear canal fusion	J:73069
	abnormal inner ear morphology	J:73069
	abnormal inner ear vestibule morphology	J:73069
	absent semicircular canals	J:73069
	circling	J:73069
	head tilt	J:73069
	hyperactivity	J:73069
	normal nervous system phenotype	J:73069
Hmx3/Hmx2^tm3Tlu/Hmx3/Hmx2^tm3Tlu either: (involves: 129) or (involves: 129 * C57BL/6J)	abnormal endolymphatic duct morphology	J:92940
	abnormal hypothalamus secretion	J:92940
	abnormal membranous labyrinth morphology	J:92940
	absent semicircular canals	J:92940
	decreased circulating growth hormone level	J:92940
	decreased vestibular hair cell number	J:92940
	impaired balance	J:92940
	muscle spasm	J:92940
	postnatal growth retardation	J:92940
	postnatal lethality, complete penetrance	J:92940
	small adenohypophysis	J:92940
	small pituitary gland	J:92940
	utricular degeneration	J:92940
	vestibular saccular degeneration	J:92940

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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