Six5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Six5
sine oculis-related homeobox 5
MGI:106220

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Six5^tm1Rdd/Six5⁺ 129S4/SvJae-Six5^tm1Rdd	abnormal testis morphology	J:91207
	increased circulating follicle stimulating hormone level	J:91207
	nuclear cataract	J:61881
	oligozoospermia	J:91207
	seminiferous tubule degeneration	J:91207
	small seminiferous tubules	J:91207
Six5^tm1Rdd/Six5⁺ involves: 129S4/SvJae * C57BL/6	cataract	J:61881
Six5^tm1Rdd/Six5^tm1Rdd 129S4/SvJae-Six5^tm1Rdd	abnormal spermatid morphology	J:91207
	abnormal spermatogenesis	J:91207
	abnormal spermiogenesis	J:91207
	abnormal testis morphology	J:91207
	azoospermia	J:91207
	decreased Sertoli cell number	J:91207
	increased circulating follicle stimulating hormone level	J:91207
	increased Leydig cell number	J:91207
	male infertility	J:91207
	nuclear cataract	J:61881
	seminiferous tubule degeneration	J:91207
	small seminiferous tubules	J:91207
	small testis	J:91207
Six5^tm1Rdd/Six5^tm1Rdd involves: 129S4/SvJae * C57BL/6	cataract	J:61881
Six5^tm1Tap/Six5⁺ involves: 129/Sv * C57BL/6	cataract	J:61882
Six5^tm1Tap/Six5^tm1Tap involves: 129/Sv * C57BL/6	cataract	J:61882
Six5^tm1Tap/Six5^tm1Tap involves: 129/Sv * C57BL/6	normal muscle phenotype	J:61882

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23