Srxn1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
MGI:104971

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Srxn1^tm1Mtol/Srxn1^tm1Mtol either: B6.129S2-Srxn1^tm1Mtol or (involves: 129S2/SvPasCrl * C57BL/6)	increased circulating alanine transaminase level	J:199277
	increased circulating aspartate transaminase level	J:199277
	increased susceptibility to endotoxin shock	J:199277
	increased susceptibility to xenobiotic induced morbidity/mortality	J:199277
Srxn1^tm1Sgrh/Srxn1^tm1Sgrh Tg(Cyp11a1-cre)16Mchu/? involves: C57BL/6J	abnormal adrenal gland secretion	J:222986
	abnormal circulating corticosterone level	J:222986
	adrenal gland hyperplasia	J:222986
	increased circulating adrenocorticotropin level	J:222986

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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