41 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gpx1tm1.1(KOMP)Vlcg/Gpx1tm1.1(KOMP)Vlcg C57BL/6N-Gpx1tm1.1(KOMP)Vlcg/Ucd	abnormal epididymis morphology	J:211773
	abnormal testis morphology	J:211773
	decreased body length	J:211773
	enlarged epididymis	J:211773
	small testis	J:211773
Gpx1tm1Kola/Gpx1tm1Kola B6.129S2(CF1)-Gpx1tm1Kola	normal immune system phenotype	J:100436
Gpx1tm1Kola/Gpx1tm1Kola involves: 129S2/SvPas * BALB/c * CF-1	abnormal response to injury	J:79183
	brain ischemia	J:71798
	increased cerebral infarct size	J:71798
	increased inflammatory response	J:79183
	increased neuron apoptosis	J:71798, J:79183
	increased susceptibility to ischemic brain injury	J:71798
	oxidative stress	J:71798
Gpx1tm1Kola/Gpx1tm1Kola involves: 129S2/SvPas * CF-1	abnormal cell cycle	J:87985
	abnormal cell morphology	J:87985
	cellular necrosis	J:87985
	decreased cell proliferation	J:87985
	increased cellular sensitivity to hydrogen peroxide	J:87985
	increased cellular sensitivity to oxidative stress	J:49644, J:87985
	normal mortality/aging	J:49644
Gpx1tm1Mgr/Gpx1tm1Mgr involves: 129 * C57BL/6J	abnormal lipid level	J:62395
	abnormal mitochondrial physiology	J:62395
	decreased body weight	J:62395
Gpx1tm1Ysh/Gpx1+ involves: 129S1/Sv * 129X1/SvJ	abnormal enzyme/coenzyme activity	J:110762
Gpx1tm1Ysh/Gpx1tm1Ysh B6.129-Gpx1tm1Ysh	abnormal jejunum crypts of Lieberkuhn morphology	J:63988
	decreased cellular sensitivity to gamma-irradiation	J:63988
Gpx1tm1Ysh/Gpx1tm1Ysh involves: 129S1/Sv * 129X1/SvJ	abnormal catalase activity	J:110762
	cataract	J:142446
	decreased glutathione peroxidase activity	J:110762
Gpx1tm1Ysh/Gpx1tm1Ysh involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal ileum crypts of Lieberkuhn morphology	J:63988
	abnormal jejunum crypts of Lieberkuhn morphology	J:63988
	abnormal platelet physiology	J:41169
	cochlear ganglion degeneration	J:113167
	cochlear inner hair cell degeneration	J:113167
	cochlear outer hair cell degeneration	J:113167
	decreased cellular sensitivity to gamma-irradiation	J:63988
	increased or absent threshold for auditory brainstem response	J:113167
	increased susceptibility to noise-induced hearing loss	J:113167
Tg(Gpx1)41Dkd/0 involves: C3H * C57BL/6	abnormal cardiovascular system physiology	J:127782
	decreased myocardial infarct size	J:127782
	increased cardiac muscle contractility	J:127782
	myocardium necrosis	J:89952, J:127782
Tg(Gpx1)41Spec/0 involves: C3H * C57BL/6	increased glutathione peroxidase activity	J:110762