Siae Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Siae
sialic acid acetylesterase
MGI:104803

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cmah^tm1Avrk/Cmah^tm1Avrk Dock2^m1Hsd/Dock2^m1Hsd Siae^tm1.2Avrk/Siae^tm1.2Avrk B6NHsd.Cg-Siae^tm1.2Avrk Dock2^m1Hsd Cmah^tm1Avrk	abnormal B cell activation	J:144035
	decreased follicular B cell number	J:144035
	decreased marginal zone B cell number	J:144035
Dock2^m1Hsd/Dock2^m1Hsd Siae^tm1.2Avrk/Siae^tm1.2Avrk B6NHsd.Cg-Siae^tm1.2Avrk Dock2^m1Hsd	abnormal B cell activation	J:144035
	abnormal immunoglobulin level	J:144035
	decreased B-1a cell number	J:144035
	decreased follicular B cell number	J:144035
	decreased marginal zone B cell number	J:144035, J:231437
	decreased T cell number	J:144035
	glomerulonephritis	J:144035
	increased anti-double stranded DNA antibody level	J:144035
	increased anti-histone antibody level	J:144035
	increased anti-single stranded DNA antibody level	J:144035
	increased B cell proliferation	J:144035
	increased B-1b cell number	J:144035
	increased CD4-positive, alpha-beta memory T cell number	J:231437
	increased IgE level	J:144035
	increased IgG1 level	J:144035
	increased IgG2a level	J:144035
	increased IgG2b level	J:144035
	increased IgG3 level	J:144035
	increased IgM level	J:144035
	renal glomerular immunoglobulin deposits	J:144035
	spleen hypoplasia	J:144035

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23