Penk Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Penk
preproenkephalin
MGI:104629

14 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Penk^tm1(KOMP)Mbp/Penk^tm1(KOMP)Mbp C57BL/6N-Penk^tm1(KOMP)Mbp/Rbrc	abnormal bone structure	J:211773
	abnormal retina morphology	J:211773
	absent testes	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased locomotor activity	J:211773
	increased total body fat amount	J:211773
Penk^tm1Dwp/Penk^tm1Dwp involves: 129 * C57BL/6J	abnormal cued conditioning behavior	J:67551
	delayed wound healing	J:67551
	increased anxiety-related response	J:67551
	increased susceptibility to induced morbidity/mortality	J:67551
Penk^tm1Jep/Penk^tm1Jep involves: 129S/SvEv * C57BL/6J	abnormal behavioral response to addictive substance	J:109209
Penk^tm1Jep/Penk^tm1Jep involves: 129S/SvEv * C57BL/6J	abnormal chemically-elicited antinociception	J:109209
Penk^tm2(cre)Hze/Penk⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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