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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
MGI:104517
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nhej1tm1Fwa/Nhej1tm1Fwa
Xrcc5tm1Nus/Xrcc5tm1Nus
involves: 129S6/SvEvTac * C57BL/6 		athymia J:236776
decreased body size J:236776
normal mortality/aging J:236776
small spleen J:236776
Paxxem1Spj/Paxxem1Spj
Xrcc5tm1Nus/Xrcc5tm1Nus
involves: C57BL/6 * C57BL/6NTac 		postnatal lethality, incomplete penetrance J:236776
Rag1tm1Mom/Rag1tm1Mom
Trp53tm1Brd/Trp53tm1Brd
Xrcc5tm1Dbr/Xrcc5tm1Dbr
involves: 129S7/SvEvBrd * C57BL 		dehydration J:141515
impaired balance J:141515
increased medulloblastoma incidence J:141515
increased sarcoma incidence J:141515
increased stomach tumor incidence J:141515
increased T cell derived lymphoma incidence J:141515
premature death J:141515
respiratory distress J:141515
Rag1tm1Mom/Rag1tm1Mom
Xrcc5tm1Dbr/Xrcc5tm1Dbr
involves: 129S7/SvEvBrd * C57BL 		increased cerebellar granule cell number J:141515
normal neoplasm J:141515
Trp53tm1Brd/Trp53tm1Brd
Xrcc5tm1Dbr/Xrcc5tm1Dbr
involves: 129S7/SvEvBrd * C57BL 		increased lymphoma incidence J:141515
increased medulloblastoma incidence J:141515
premature death J:141515
Xrcc5tm1Dbr/Xrcc5+
Lig4tm1Fwa/Lig4+
involves: 129S6/SvEvTac * C57BL/6 		chromosome breakage J:80467
Xrcc5tm1Dbr/Xrcc5tm1Dbr
Lig4tm1Fwa/Lig4tm1Fwa
involves: 129S6/SvEvTac * C57BL/6 		abnormal lymphocyte morphology J:80467
abnormal small intestine morphology J:80467
chromosome breakage J:80467
normal mortality/aging J:80467
prenatal lethality, incomplete penetrance J:80467
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory