Cxcr5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cxcr5
C-X-C motif chemokine receptor 5
MGI:103567

18 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcr5^tm1.1Namt/Cxcr5^tm1.1Namt involves: C57BL/6J	no abnormal phenotype detected	J:241561
Cxcr5^tm1.1Namt/Cxcr5^tm1.1Namt Tg(Itgax-cre)1-1Reiz/0 involves: C57BL/6 * C57BL/6J * CBA	abnormal dendritic cell chemotaxis	J:241561
	decreased follicular dendritic cell number	J:241561
	decreased susceptibility to prion infection	J:241561
	normal immune system phenotype	J:241561
Cxcr5^tm1Lipp/Cxcr5^tm1Lipp involves: 129S2/SvPas * CD-1	abnormal leukocyte migration	J:37126
	abnormal Peyer's patch morphology	J:37126
	abnormal spleen primary B follicle morphology	J:37126
	abnormal spleen secondary B follicle morphology	J:37126
	absent axillary lymph nodes	J:78282
	absent brachial lymph nodes	J:78282
	absent cervical lymph nodes	J:78282
	absent follicular dendritic cells	J:78282
	absent inguinal lymph nodes	J:37126, J:78282
	absent lymph nodes	J:78282
	absent Peyer's patches	J:37126
	absent spleen germinal center	J:37126
	increased B cell number	J:37126

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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