Rbl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbl1
RB transcriptional corepressor like 1
MGI:103300

48 phenotypes from 6 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rbl1^tm1.1Fad/Rbl1^tm1.1Fad involves: 129 * FVB/N	normal cellular phenotype	J:217445
Rbl1^{tm1b(EUCOMM)Hmgu}/Rbl1⁺ C57BL/6N-Rbl1^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal kidney morphology	J:211773
	improved glucose tolerance	J:211773
	shortened QRS complex duration	J:211773
Rbl1^{tm1b(EUCOMM)Hmgu}/Rbl1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Rbl1^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, incomplete penetrance	J:211773
Rbl1^tm1Htr/Rbl1^tm1Htr Tg(Chx10-EGFP/cre,-ALPP)2Clc/? involves: 129 * C57BL/6 * FVB/N * NMRI * SJL	abnormal amacrine cell morphology	J:124204
Rbl1^tm1Htr/Rbl1^tm1Htr Tg(Pax6-cre,GFP)2Pgr/? involves: 129 * C57BL/6 * FVB/N * NMRI	abnormal amacrine cell morphology	J:124204
	abnormal cone electrophysiology	J:124204
	abnormal eye development	J:124204
	abnormal optic nerve morphology	J:124204
	abnormal retina bipolar cell morphology	J:124204
	abnormal retina inner nuclear layer morphology	J:124204
	abnormal retina inner plexiform layer morphology	J:124204
	abnormal retina morphology	J:124204
	abnormal rod electrophysiology	J:124204
	decreased retina ganglion cell number	J:124204
	decreased retina rod cell number	J:124204
	thin retina outer nuclear layer	J:124204
Rbl1^tm1Mru/Rbl1^tm1Mru involves: 129S4/SvJae * BALB/c	abnormal white adipose tissue morphology	J:129672
	decreased body size	J:129672
	decreased gonadal fat pad weight	J:129672
	decreased inguinal fat pad weight	J:129672
	decreased interscapular fat pad weight	J:129672
	decreased percent body fat/body weight	J:129672
	decreased total fat pad weight	J:129672
	decreased white adipose tissue amount	J:129672
	decreased white fat cell size	J:129672
	hepatic steatosis	J:129672
	increased oxygen consumption	J:129672
	postnatal lethality, incomplete penetrance	J:129672
Rbl1^tm1Mru/Rbl1^tm1Mru involves: 129S4/SvJae * BALB/c * C57BL/6	abnormal neuronal precursor proliferation	J:92520
	abnormal postnatal subventricular zone morphology	J:92520
	increased neuronal precursor cell number	J:92520
Rbl1^tm1Mru/Rbl1^tm1Mru involves: 129S4/SvJae * BALB/cJ	abnormal common myeloid progenitor cell morphology	J:51060
	abnormal definitive hematopoiesis	J:51060
	abnormal inflammatory response	J:51060
	abnormal muscle physiology	J:51060
	abnormal spleen red pulp morphology	J:51060
	decreased body size	J:51060
	decreased body weight	J:51060
	extramedullary hematopoiesis	J:51060
	increased bone marrow cell number	J:51060
	increased cell proliferation	J:51060
	increased fibroblast proliferation	J:51060
	postnatal growth retardation	J:51060
	premature death	J:51060
	spontaneous skin ulceration	J:51060
Rbl1^tm1Mru/Rbl1^tm1Mru involves: 129S4/SvJae * BALB/cJ * C57BL/6J	decreased body size	J:51060
Rbl1^tm1Tyj/Rbl1⁺ involves: 129S2/SvPas * C57BL/6	no abnormal phenotype detected	J:34058
Rbl1^tm1Tyj/Rbl1^tm1Tyj involves: 129S2/SvPas	increased diameter of long bones	J:34725
Rbl1^tm1Tyj/Rbl1^tm1Tyj involves: 129S2/SvPas * C57BL/6	normal cellular phenotype	J:34058
	normal integument phenotype	J:82802
	no abnormal phenotype detected	J:34058
Rbl1^tm3.1Jsag/Rbl1^tm3.1Jsag involves: C57BL/6	increased fibroblast proliferation	J:161509

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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