Dsc2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dsc2
desmocollin 2
MGI:103221

16 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dsc2^tm1.1Leu/Dsc2^tm1.1Leu Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	normal digestive/alimentary phenotype	J:302333
	normal growth/size/body region phenotype	J:302333
	normal immune system phenotype	J:302333
Dsc2^tm1.2Leu/Dsc2^tm1.2Leu involves: C57BL/6	cardiac fibrosis	J:302593
	cardiac hypertrophy	J:302593
	normal cardiovascular system phenotype	J:302593
	decreased heart left ventricle muscle contractility	J:302593
	normal embryo phenotype	J:302593
	normal growth/size/body region phenotype	J:302593
	heart left ventricle hypertrophy	J:302593
	increased apoptosis	J:302593
	normal mortality/aging	J:302593
	normal reproductive system phenotype	J:302593
Dsc2^{tm1e(KOMP)Wtsi}/Dsc2^{tm1e(KOMP)Wtsi} C57BL/6N-Dsc2^{tm1e(KOMP)Wtsi}/Wtsi	abnormal cornea morphology	J:211773
	cornea opacity	J:211773
	cornea vascularization	J:211773
	narrow eye opening	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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