F10 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F10
coagulation factor X
MGI:103107

15 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F10^{tm1b(EUCOMM)Hmgu}/F10⁺ C57BL/6N-F10^{tm1b(EUCOMM)Hmgu}/H	decreased circulating creatinine level	J:211773
	increased grip strength	J:211773
	increased kidney weight	J:211773
F10^{tm1b(EUCOMM)Hmgu}/F10^{tm1b(EUCOMM)Hmgu} C57BL/6N-F10^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, complete penetrance	J:211773
F10^tm1Ccmt/F10^tm1Ccmt involves: 129P2/OlaHsd * C57BL/6	embryonic lethality during organogenesis, incomplete penetrance	J:145092
	increased bleeding time	J:145092
	internal hemorrhage	J:145092
	neonatal lethality	J:145092
F10^tm1Ccmt/F10^tm2Ccmt involves: 129P2/OlaHsd * C57BL/6	decreased litter size	J:145092
F10^tm1Edr/F10^tm1Edr involves: 129S1/Sv * 129X1/SvJ * Swiss	normal cardiovascular system phenotype	J:61230
	embryonic lethality during organogenesis, incomplete penetrance	J:61230
	internal hemorrhage	J:61230
	neonatal lethality, incomplete penetrance	J:61230
	postnatal lethality, complete penetrance	J:61230
F10^tm2Ccmt/F10^tm2Ccmt involves: 129P2/OlaHsd * C57BL/6	cardiac fibrosis	J:145092
	increased heart iron level	J:145092
	normal mortality/aging	J:145092

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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