Atrx Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atrx
ATRX, chromatin remodeler
MGI:103067

35 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atrx^{Gt(E085A04)Wrst}/Y chimera involves: 129P2/OlaHsd	abnormal developmental patterning	J:160967
Atrx^{Gt(E085A04)Wrst}/Y chimera involves: 129P2/OlaHsd	embryonic lethality during organogenesis, complete penetrance	J:160967
Atrx^{Gt(P034C09)Wrst}/Y chimera involves: 129S6/SvEvTac * C57BL/6	abnormal developmental patterning	J:160967
Atrx^{Gt(P034D09)Wrst}/Y chimera involves: 129S6/SvEvTac * C57BL/6J	abnormal developmental patterning	J:160967
	abnormal heart morphology	J:160967
Atrx^tm1Enl/Atrx^tm1Enl B6.129S4-Atrx^tm1Enl	normal behavior/neurological phenotype	J:168608
	decreased body weight	J:168608
	impaired contextual conditioning behavior	J:168608
	prenatal lethality, incomplete penetrance	J:168608
	reduced long-term potentiation	J:168608
Atrx^tm1Rjg/Atrx⁺ Tg(Gata1-cre)1Sho/0 involves: 129P2/OlaHsd * C57BL/6 * CD-1	abnormal behavior	J:115836
	abnormal imprinting	J:115836
	abnormal reproductive system physiology	J:115836
	embryonic lethality during organogenesis, incomplete penetrance	J:115836
Atrx^tm1Rjg/Y Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal suckling behavior	J:95953
	absent dentate gyrus	J:95953
	absent gastric milk in neonates	J:95953
	decreased birth body size	J:95953
	decreased hippocampus pyramidal cell number	J:95953
	loss of cortex neurons	J:95953
	loss of hippocampal neurons	J:95953
	postnatal lethality, complete penetrance	J:95953
Atrx^tm1Rjg/Y Tg(Gata1-cre)1Sho/0 involves: 129P2/OlaHsd * C57BL/6 * CD-1	abnormal ectoplacental cone morphology	J:115836
	abnormal trophectoderm morphology	J:115836
	decreased cell proliferation	J:115836
	decreased embryo size	J:115836
	decreased trophoblast giant cell number	J:115836
	disorganized extraembryonic tissue	J:115836
	embryonic growth retardation	J:115836
	embryonic lethality during organogenesis, complete penetrance	J:115836
	small ectoplacental cone	J:115836
Atrx^tm1Rjg/Y Tg(Nes-cre)2472Pick/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	decreased birth body size	J:95953
	loss of cortex neurons	J:95953
	loss of hippocampal neurons	J:95953
	postnatal lethality, incomplete penetrance	J:95953
Atrx^tm1Rjg/Y Tg(Pax6-cre,GFP)2Pgr/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal eye electrophysiology	J:145002
	abnormal retina ganglion layer morphology	J:145002
	abnormal retina horizontal cell morphology	J:145002
	abnormal retina inner nuclear layer morphology	J:145002
	abnormal retina morphology	J:145002
	decreased amacrine cell number	J:145002

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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