Klra8 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klra8
killer cell lectin-like receptor, subfamily A, member 8
MGI:102968

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Klra8^Cmv1-del/Klra8^Cmv1-r (BXD8/TyJ x C57BL/6)F1	decreased susceptibility to Herpesvirales infection	J:79093
Klra8^Cmv1-del/Klra8^Cmv1-s (BXD8/TyJ x BALB/c)F1	increased susceptibility to Herpesvirales infection	J:79093
Klra8^Cmv1-del/Klra8^Cmv1-s (BXD8/TyJ x DBA/2)F1	increased susceptibility to Herpesvirales infection	J:79093
Klra8^Cmv1-r/Klra8^Cmv1-r C.B6-Klra8^Cmv1-r	decreased IgG1 level	J:97203
	decreased IgG2a level	J:97203
	decreased IgG2b level	J:97203
	decreased IgG3 level	J:97203
	decreased IgG level	J:97203
	decreased interleukin-4 secretion	J:97203
	decreased susceptibility to Herpesvirales infection	J:22486, J:79093
	decreased transforming growth factor beta level	J:97203
	increased circulating interferon-gamma level	J:97203
	increased IgM level	J:97203
	increased susceptibility to infection induced morbidity/mortality	J:97203
	increased susceptibility to parasitic infection	J:97203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23