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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Txk
TXK tyrosine kinase
MGI:102960
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Itktm1Litt/Itktm1Litt
Txktm1Pls/Txktm1Pls
involves: 129S4/SvJae * 129S6/SvEvTac
decreased CD4-positive, alpha-beta T cell number J:54449
decreased single-positive T cell number J:54449
decreased T cell proliferation J:54449
increased susceptibility to parasitic infection J:54449
Itktm1Ljb/Itktm1Ljb
Txktm1Pls/Txktm1Pls
B6.129-Txktm1Pls Itktm1Ljb
abnormal CD8-positive, alpha-beta T cell physiology J:113408
increased CD8-positive, alpha-beta T cell number J:113408
increased interferon-gamma secretion J:113408
increased memory T cell number J:113408

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory