35 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd86tm1Shr/Cd86tm1Shr B6.129S4-Cd86tm1Shr	decreased T cell proliferation	J:57613
	increased interferon-gamma secretion	J:57613
Cd86tm1Shr/Cd86tm1Shr involves: 129S4/SvJae	abnormal humoral immune response	J:39089
	absent spleen germinal center	J:39089
	decreased IgG level	J:39089
Cd86tm1Shr/Cd86tm1Shr NOD.129S4-Cd86tm1Shr	abnormal action potential	J:71352
	abnormal dorsal root ganglion morphology	J:71352
	abnormal dorsal spinal root morphology	J:71352
	abnormal myelin sheath morphology	J:71352
	abnormal nerve conduction	J:71352, J:142046
	abnormal nervous system morphology	J:71352
	abnormal T cell proliferation	J:142046
	abnormal ventral spinal root morphology	J:71352
	decreased grip strength	J:142046
	decreased nerve conduction velocity	J:142046
	decreased regulatory T cell number	J:93421
	decreased susceptibility to autoimmune diabetes	J:71352
	decreased T cell proliferation	J:93421
	demyelination	J:71352
	hindlimb paralysis	J:71352
	increased autoantibody level	J:142046
	increased interferon-gamma secretion	J:142046
	increased susceptibility to autoimmune diabetes	J:93421
	muscular atrophy	J:71352
	paresis	J:142046
Tg(H2-K-Cd86)7All/0 B6.Cg-Tg(H2-K-Cd86)7All	abnormal inflammatory response	J:112266
	decreased B cell number	J:112266
	decreased CD4-positive, alpha-beta T cell number	J:112266
	increased CD8-positive, alpha-beta T cell number	J:112266
	increased T cell number	J:112266
	lymph node hyperplasia	J:112266
	lymphoid hyperplasia	J:112266
Tg(H2-K-Cd86)7All/0 involves: BALB/c * C57BL/6 * CBA	increased splenocyte number	J:112266
	lymph node hyperplasia	J:112266
	spleen hyperplasia	J:112266
Tg(H2-K-Cd86)7All/0 involves: C57BL/6J * CBA	abnormal B cell differentiation	J:112475
	decreased B cell number	J:112475
	increased CD4-positive, alpha-beta T cell number	J:112475
	increased CD8-positive, alpha-beta T cell number	J:112475
Tg(H2-K-Cd86)27All/0 involves: C57BL/6J * CBA	abnormal B cell differentiation	J:112475
	decreased B cell number	J:112475
Tg(H2-K-Cd86)31All/0 involves: C57BL/6J * CBA	increased CD4-positive, alpha-beta T cell number	J:112475
	increased CD8-positive, alpha-beta T cell number	J:112475
Tg(Igh-6-Cd86)1Akab/0 involves: FVB	abnormal CD4-positive, alpha-beta T cell physiology	J:44271
	decreased B cell number	J:44271