Kcnma1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
MGI:99923

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0015269	calcium-activated potassium channel activity	ISO	J:155856
Molecular Function	GO:0015269	calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0015269	calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0015269	calcium-activated potassium channel activity	TAS	Reactome:R-MMU-9667762
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IGI	J:82065
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IGI	J:82065
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:118875
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:57916
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:104394
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IDA	J:13395
Molecular Function	GO:0015269	calcium-activated potassium channel activity	IMP	J:92539
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IDA	J:118875
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	IMP	J:207964
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	ISO	J:155856
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	IBA	J:265628
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	IMP	J:116922
Molecular Function	GO:0060072	large conductance calcium-activated potassium channel activity	IDA	J:82065
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005267	potassium channel activity	IGI	J:116922
Molecular Function	GO:0005267	potassium channel activity	IMP	J:117811
Molecular Function	GO:0005515	protein binding	IPI	J:150861
Molecular Function	GO:0005515	protein binding	IPI	J:150861
Molecular Function	GO:0005515	protein binding	IPI	J:153765
Molecular Function	GO:0005515	protein binding	IPI	J:200426
Molecular Function	GO:0005515	protein binding	IPI	J:248287
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005249	voltage-gated potassium channel activity	TAS	Reactome:R-MMU-9667756
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IMP	J:92539
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:13395
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:117811
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:118875
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:118875
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:82065
Cellular Component	GO:0016020	membrane	IC	J:13395
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9667756
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9667762
Cellular Component	GO:0005886	plasma membrane	IDA	J:57916
Cellular Component	GO:0005886	plasma membrane	IDA	J:86594
Cellular Component	GO:0045211	postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:92443
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0016528	sarcoplasm	IDA	J:86594
Cellular Component	GO:0043195	terminal bouton	IDA	J:92443
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IGI	J:82065
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IGI	J:82065
Biological Process	GO:0007628	adult walking behavior	IMP	J:92539
Biological Process	GO:0007628	adult walking behavior	IMP	J:91427
Biological Process	GO:0097746	blood vessel diameter maintenance	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:91427
Biological Process	GO:0007623	circadian rhythm	IMP	J:111722
Biological Process	GO:0002069	columnar/cuboidal epithelial cell maturation	IMP	J:92443
Biological Process	GO:0060082	eye blink reflex	IMP	J:91427
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:92443
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:117764
Biological Process	GO:0030007	intracellular potassium ion homeostasis	ISO	J:164563
Biological Process	GO:0045475	locomotor rhythm	IMP	J:111722
Biological Process	GO:0060073	micturition	ISO	J:164563
Biological Process	GO:0060073	micturition	IMP	J:92539
Biological Process	GO:0060073	micturition	IMP	J:92539
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0045794	negative regulation of cell volume	ISO	J:164563
Biological Process	GO:0045794	negative regulation of cell volume	IMP	J:116922
Biological Process	GO:1904348	negative regulation of small intestine smooth muscle contraction	ISO	J:155856
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:92539
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:91427
Biological Process	GO:0042551	neuron maturation	IMP	J:92443
Biological Process	GO:0019228	neuronal action potential	IMP	J:111722
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006813	potassium ion transport	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	IDA	J:13395
Biological Process	GO:0006813	potassium ion transport	IDA	J:57916
Biological Process	GO:0032344	regulation of aldosterone metabolic process	IMP	J:116177
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	IDA	J:13395
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:109217
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:91427
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0060087	relaxation of vascular associated smooth muscle	IMP	J:116777
Biological Process	GO:0051592	response to calcium ion	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	ISO	J:164563
Biological Process	GO:0034465	response to carbon monoxide	ISO	J:164563
Biological Process	GO:0031960	response to corticosteroid	ISO	J:155856
Biological Process	GO:0043627	response to estrogen	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0001666	response to hypoxia	ISO	J:164563
Biological Process	GO:0001666	response to hypoxia	IDA	J:104394
Biological Process	GO:0006970	response to osmotic stress	ISO	J:164563
Biological Process	GO:0009268	response to pH	ISO	J:155856
Biological Process	GO:0046541	saliva secretion	IGI	J:116922
Biological Process	GO:0007605	sensory perception of sound	IMP	J:109217
Biological Process	GO:0007605	sensory perception of sound	IMP	J:92443
Biological Process	GO:0060083	smooth muscle contraction involved in micturition	ISO	J:164563
Biological Process	GO:0060083	smooth muscle contraction involved in micturition	IMP	J:104666
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0042311	vasodilation	ISO	J:155856
Biological Process	GO:0042311	vasodilation	IMP	J:116777

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