GO Annotations Graph

• Symbol: Adcy3
• Name: adenylate cyclase 3
• ID: MGI:99675

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004016	adenylate cyclase activity	ISO	J:155856
Molecular Function	GO:0004016	adenylate cyclase activity	IMP	J:64745
Molecular Function	GO:0004016	adenylate cyclase activity	TAS	Reactome:R-MMU-9713712
Molecular Function	GO:0004016	adenylate cyclase activity	IBA	J:265628
Molecular Function	GO:0004016	adenylate cyclase activity	TAS	J:22804
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016849	phosphorus-oxygen lyase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:78798
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0060170	ciliary membrane	IDA	J:237910
Cellular Component	GO:0005929	cilium	ISO	J:155856
Cellular Component	GO:0005929	cilium	IDA	J:64745
Cellular Component	GO:0005929	cilium	IDA	J:178978
Cellular Component	GO:0005929	cilium	IDA	J:190988
Cellular Component	GO:0005929	cilium	IDA	J:246963
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:64745
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9713712
Cellular Component	GO:0005886	plasma membrane	TAS	J:22804
Biological Process	GO:0007340	acrosome reaction	IMP	J:97802
Biological Process	GO:0007190	activation of adenylate cyclase activity	TAS	J:22804
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IMP	J:64745
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0006171	cAMP biosynthetic process	ISO	J:155856
Biological Process	GO:0006171	cAMP biosynthetic process	IMP	J:64745
Biological Process	GO:0006171	cAMP biosynthetic process	IBA	J:265628
Biological Process	GO:1904322	cellular response to forskolin	ISO	J:155856
Biological Process	GO:1904322	cellular response to forskolin	IMP	J:64745
Biological Process	GO:0009190	cyclic nucleotide biosynthetic process	IEA	J:72247
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:97802
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0008355	olfactory learning	IMP	J:64745
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0007608	sensory perception of smell	IMP	J:64745
Biological Process	GO:0007608	sensory perception of smell	IDA	J:190988
Biological Process	GO:0007338	single fertilization	IMP	J:97802