GO Annotations Graph

• Symbol: Ephx2
• Name: epoxide hydrolase 2, cytoplasmic
• ID: MGI:99500

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0033885	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity	IEA	J:72245
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004301	epoxide hydrolase activity	IMP	J:170657
Molecular Function	GO:0004301	epoxide hydrolase activity	ISO	J:155856
Molecular Function	GO:0004301	epoxide hydrolase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042577	lipid phosphatase activity	ISO	J:164563
Molecular Function	GO:0042577	lipid phosphatase activity	IBA	J:265628
Molecular Function	GO:0052642	lysophosphatidic acid phosphatase activity	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:155856
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016791	phosphatase activity	ISO	J:155856
Molecular Function	GO:0016791	phosphatase activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0015643	toxic substance binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	ISO	J:155856
Cellular Component	GO:0005777	peroxisome	IBA	J:265628
Biological Process	GO:0019439	aromatic compound catabolic process	IEA	J:60000
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IDA	J:143932
Biological Process	GO:0042632	cholesterol homeostasis	IBA	J:265628
Biological Process	GO:0016311	dephosphorylation	ISO	J:164563
Biological Process	GO:0097176	epoxide metabolic process	ISO	J:155856
Biological Process	GO:0097176	epoxide metabolic process	ISO	J:164563
Biological Process	GO:0097176	epoxide metabolic process	IMP	J:170657
Biological Process	GO:0006954	inflammatory response	ISO	J:155856
Biological Process	GO:0043651	linoleic acid metabolic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0046839	phospholipid dephosphorylation	ISO	J:164563
Biological Process	GO:0046839	phospholipid dephosphorylation	IBA	J:265628
Biological Process	GO:0045777	positive regulation of blood pressure	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:143932
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0002539	prostaglandin production involved in inflammatory response	ISO	J:155856
Biological Process	GO:0090181	regulation of cholesterol metabolic process	IMP	J:143932
Biological Process	GO:0090181	regulation of cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0009636	response to toxic substance	IEA	J:60000
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0046272	stilbene catabolic process	ISO	J:164563