GO Annotations Graph

• Symbol: Sord
• Name: sorbitol dehydrogenase
• ID: MGI:98266

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	IDA	J:7208
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	IMP	J:44612
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	IMP	J:106587
Molecular Function	GO:0046526	D-xylulose reductase activity	IDA	J:323240
Molecular Function	GO:0046526	D-xylulose reductase activity	ISO	J:323241
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IMP	J:106587
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IDA	J:7208
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IMP	J:44612
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IDA	J:441
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IDA	J:7055
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IDA	J:12039
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	IDA	J:7208
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051287	NAD binding	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:7208
Cellular Component	GO:0005829	cytosol	IDA	J:323240
Cellular Component	GO:0005829	cytosol	IDA	J:76552
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:145793
Cellular Component	GO:0031514	motile cilium	IDA	J:145793
Biological Process	GO:0030317	flagellated sperm motility	IDA	J:145793
Biological Process	GO:0046370	fructose biosynthetic process	ISO	J:164563
Biological Process	GO:0046370	fructose biosynthetic process	IMP	J:106587
Biological Process	GO:0046370	fructose biosynthetic process	IDA	J:145793
Biological Process	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate	IDA	J:323240
Biological Process	GO:0051160	L-xylitol catabolic process	ISO	J:164563
Biological Process	GO:0051164	L-xylitol metabolic process	ISO	J:164563
Biological Process	GO:0046686	response to cadmium ion	ISO	J:155856
Biological Process	GO:0046688	response to copper ion	ISO	J:155856
Biological Process	GO:0009725	response to hormone	ISO	J:155856
Biological Process	GO:0006062	sorbitol catabolic process	ISO	J:164563
Biological Process	GO:0006062	sorbitol catabolic process	IBA	J:265628
Biological Process	GO:0006060	sorbitol metabolic process	IDA	J:12039
Biological Process	GO:0006060	sorbitol metabolic process	IDA	J:7208