GO Annotations Graph

• Symbol: Psap
• Name: prosaposin
• ID: MGI:97783

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	IPI	J:213894
Molecular Function	GO:1905573	ganglioside GM1 binding	ISO	J:164563
Molecular Function	GO:1905574	ganglioside GM2 binding	ISO	J:164563
Molecular Function	GO:1905575	ganglioside GM3 binding	ISO	J:164563
Molecular Function	GO:1905577	ganglioside GP1c binding	ISO	J:164563
Molecular Function	GO:1905576	ganglioside GT1b binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:84480
Molecular Function	GO:0030882	lipid antigen binding	IDA	J:90443
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0002020	protease binding	ISO	J:216017
Molecular Function	GO:0005515	protein binding	IPI	J:227553
Molecular Function	GO:0005515	protein binding	IPI	J:227553
Molecular Function	GO:0005515	protein binding	IPI	J:250451
Molecular Function	GO:0005515	protein binding	IPI	J:116349
Molecular Function	GO:0005515	protein binding	IPI	J:90443
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Cellular Component	GO:0016235	aggresome	IDA	J:162691
Cellular Component	GO:0005737	cytoplasm	IDA	J:154468
Cellular Component	GO:0005737	cytoplasm	IDA	J:182747
Cellular Component	GO:0005576	extracellular region	IDA	J:250451
Cellular Component	GO:0005576	extracellular region	IDA	J:154468
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IDA	J:154468
Cellular Component	GO:0005764	lysosome	IDA	J:84480
Cellular Component	GO:0005764	lysosome	IDA	J:261411
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0032991	protein-containing complex	ISO	J:162691
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	J:213894
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0019882	antigen processing and presentation	IMP	J:90443
Biological Process	GO:0071310	cellular response to organic substance	IMP	J:137650
Biological Process	GO:0071310	cellular response to organic substance	IMP	J:137650
Biological Process	GO:0006672	ceramide metabolic process	IMP	J:121761
Biological Process	GO:0006672	ceramide metabolic process	IMP	J:94408
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:94408
Biological Process	GO:0090102	cochlea development	IMP	J:116349
Biological Process	GO:0003335	corneocyte development	IMP	J:216017
Biological Process	GO:0003335	corneocyte development	IMP	J:216017
Biological Process	GO:1903575	cornified envelope assembly	IMP	J:216017
Biological Process	GO:0048589	developmental growth	IMP	J:106511
Biological Process	GO:0048589	developmental growth	IMP	J:106511
Biological Process	GO:0048589	developmental growth	IMP	J:106511
Biological Process	GO:0048589	developmental growth	IMP	J:106511
Biological Process	GO:0048589	developmental growth	IMP	J:106511
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	IBA	J:265628
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	IMP	J:106511
Biological Process	GO:0006683	galactosylceramide catabolic process	IMP	J:78223
Biological Process	GO:1905572	ganglioside GM1 transport to membrane	ISO	J:164563
Biological Process	GO:0010467	gene expression	IMP	J:240061
Biological Process	GO:0010467	gene expression	IDA	J:240061
Biological Process	GO:0006678	glucosylceramide metabolic process	IMP	J:121761
Biological Process	GO:0006664	glycolipid metabolic process	IMP	J:120657
Biological Process	GO:0070841	inclusion body assembly	IMP	J:113052
Biological Process	GO:0006886	intracellular protein transport	IMP	J:121761
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:1905146	lysosomal protein catabolic process	IMP	J:85068
Biological Process	GO:0007041	lysosomal transport	ISO	J:164563
Biological Process	GO:0006643	membrane lipid metabolic process	IDA	J:90443
Biological Process	GO:0060073	micturition	IMP	J:78223
Biological Process	GO:0042552	myelination	IMP	J:78223
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	IDA	J:213894
Biological Process	GO:0050877	nervous system process	IMP	J:113052
Biological Process	GO:0050877	nervous system process	IMP	J:121761
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:182747
Biological Process	GO:0001865	NK T cell differentiation	IMP	J:90443
Biological Process	GO:1903771	positive regulation of beta-galactosidase activity	ISO	J:164563
Biological Process	GO:0051345	positive regulation of hydrolase activity	IMP	J:78223
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:213894
Biological Process	GO:0060736	prostate gland growth	IBA	J:265628
Biological Process	GO:0060736	prostate gland growth	IMP	J:106511
Biological Process	GO:0009306	protein secretion	IMP	J:121761
Biological Process	GO:0019216	regulation of lipid metabolic process	IBA	J:265628
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:137650
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:137650
Biological Process	GO:0043408	regulation of MAPK cascade	IMP	J:106511
Biological Process	GO:0072001	renal system development	IMP	J:94408
Biological Process	GO:0007605	sensory perception of sound	IMP	J:116349
Biological Process	GO:0007605	sensory perception of sound	IMP	J:182747
Biological Process	GO:0006665	sphingolipid metabolic process	IMP	J:78223
Biological Process	GO:0090659	walking behavior	IMP	J:182747