Pmp22 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pmp22
peripheral myelin protein 22
MGI:97631

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003774	cytoskeletal motor activity	IMP	J:259163
Molecular Function	GO:0005515	protein binding	IPI	J:261524
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Molecular Function	GO:0005515	protein binding	IPI	J:235660
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:104989
Cellular Component	GO:0043218	compact myelin	ISO	J:155856
Cellular Component	GO:0043218	compact myelin	IDA	J:118023
Cellular Component	GO:0043218	compact myelin	IDA	J:261524
Cellular Component	GO:0008305	integrin complex	IDA	J:104989
Cellular Component	GO:0043256	laminin complex	IDA	J:104989
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:79382
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:79382
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:235660
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:218183
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:79382
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:79382
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:215632
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:79382
Biological Process	GO:0007628	adult walking behavior	IMP	J:79382
Biological Process	GO:0007628	adult walking behavior	IMP	J:79382
Biological Process	GO:0007628	adult walking behavior	IMP	J:79382
Biological Process	GO:0070842	aggresome assembly	IMP	J:97015
Biological Process	GO:0006914	autophagy	IMP	J:215632
Biological Process	GO:0006914	autophagy	IMP	J:97418
Biological Process	GO:0006914	autophagy	IMP	J:119095
Biological Process	GO:0061564	axon development	IMP	J:157710
Biological Process	GO:0071711	basement membrane organization	IMP	J:104989
Biological Process	GO:0032060	bleb assembly	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IMP	J:218183
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	ISO	J:155856
Biological Process	GO:0044255	cellular lipid metabolic process	IMP	J:181551
Biological Process	GO:0051641	cellular localization	IMP	J:98231
Biological Process	GO:0034605	cellular response to heat	IMP	J:202239
Biological Process	GO:0034620	cellular response to unfolded protein	IMP	J:202239
Biological Process	GO:0008203	cholesterol metabolic process	IMP	J:218183
Biological Process	GO:0010761	fibroblast migration	IMP	J:218183
Biological Process	GO:0042063	gliogenesis	IMP	J:97418
Biological Process	GO:0006955	immune response	IMP	J:181551
Biological Process	GO:0030032	lamellipodium assembly	IMP	J:218183
Biological Process	GO:0007618	mating	IMP	J:104989
Biological Process	GO:0031579	membrane raft organization	IMP	J:218813
Biological Process	GO:0061744	motor behavior	IMP	J:79382
Biological Process	GO:0061744	motor behavior	IMP	J:79382
Biological Process	GO:0061744	motor behavior	IMP	J:79382
Biological Process	GO:0061744	motor behavior	IMP	J:104989
Biological Process	GO:0035264	multicellular organism growth	IMP	J:104989
Biological Process	GO:0055001	muscle cell development	IMP	J:259163
Biological Process	GO:0032288	myelin assembly	IBA	J:265628
Biological Process	GO:0032288	myelin assembly	IMP	J:217815
Biological Process	GO:0032288	myelin assembly	IMP	J:159829
Biological Process	GO:0032288	myelin assembly	IMP	J:157710
Biological Process	GO:0032288	myelin assembly	IMP	J:235660
Biological Process	GO:0032288	myelin assembly	IMP	J:105898
Biological Process	GO:0042552	myelination	ISO	J:155856
Biological Process	GO:0042552	myelination	IMP	J:166463
Biological Process	GO:0042552	myelination	IMP	J:259163
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:261524
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:162328
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:181551
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:162328
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:162328
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:79382
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:215632
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:104989
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:217815
Biological Process	GO:0022011	myelination in peripheral nervous system	IMP	J:218183
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:202239
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0098529	neuromuscular junction development, skeletal muscle fiber	IMP	J:215632
Biological Process	GO:0050905	neuromuscular process	IMP	J:79382
Biological Process	GO:0019228	neuronal action potential	IMP	J:235660
Biological Process	GO:0019227	neuronal action potential propagation	IMP	J:157710
Biological Process	GO:0045161	neuronal ion channel clustering	IMP	J:98231
Biological Process	GO:0030913	paranodal junction assembly	IMP	J:104989
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:104989
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:181551
Biological Process	GO:0007422	peripheral nervous system development	IMP	J:121259
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	IMP	J:215632
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	IMP	J:79382
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	IMP	J:79382
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	IMP	J:79382
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:104989
Biological Process	GO:0010498	proteasomal protein catabolic process	IMP	J:97418
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	J:97015
Biological Process	GO:2001233	regulation of apoptotic signaling pathway	IMP	J:202239
Biological Process	GO:0010468	regulation of gene expression	IMP	J:218183
Biological Process	GO:0010468	regulation of gene expression	IMP	J:259163
Biological Process	GO:0034350	regulation of glial cell apoptotic process	IMP	J:102207
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:202239
Biological Process	GO:0071900	regulation of protein serine/threonine kinase activity	IMP	J:235660
Biological Process	GO:0010624	regulation of Schwann cell proliferation	IMP	J:102207
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:202239
Biological Process	GO:0014044	Schwann cell development	IMP	J:218183
Biological Process	GO:0014037	Schwann cell differentiation	IMP	J:259163
Biological Process	GO:0014037	Schwann cell differentiation	IMP	J:227754
Biological Process	GO:0014037	Schwann cell differentiation	IMP	J:97015
Biological Process	GO:0014037	Schwann cell differentiation	IMP	J:97418
Biological Process	GO:0036135	Schwann cell migration	IMP	J:218183
Biological Process	GO:0051146	striated muscle cell differentiation	IMP	J:104989
Biological Process	GO:0019226	transmission of nerve impulse	IGI	J:235660
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:259163
Biological Process	GO:0019226	transmission of nerve impulse	IGI	J:261524
Biological Process	GO:0019226	transmission of nerve impulse	IGI	J:162328
Biological Process	GO:0019226	transmission of nerve impulse	IGI	J:162328
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:101812
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:157710
Biological Process	GO:0060005	vestibular reflex	IMP	J:79382
Biological Process	GO:0060005	vestibular reflex	IMP	J:79382
Biological Process	GO:0060005	vestibular reflex	IMP	J:79382

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23