GO Annotations Graph

• Symbol: Pmch
• Name: pro-melanin-concentrating hormone
• ID: MGI:97629

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0030354	melanin-concentrating hormone activity	NAS	J:81787
Molecular Function	GO:0005102	signaling receptor binding	NAS	J:81787
Molecular Function	GO:0031777	type 1 melanin-concentrating hormone receptor binding	ISO	J:155856
Molecular Function	GO:0031777	type 1 melanin-concentrating hormone receptor binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:33138
Biological Process	GO:0007610	behavior	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IEA	J:72247
Biological Process	GO:0042756	drinking behavior	ISO	J:155856
Biological Process	GO:0007631	feeding behavior	ISO	J:155856
Biological Process	GO:0007631	feeding behavior	IMP	J:81787
Biological Process	GO:0042593	glucose homeostasis	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0032227	negative regulation of synaptic transmission, dopaminergic	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	IEA	J:60000
Biological Process	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0002027	regulation of heart rate	ISO	J:155856
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	ISO	J:155856
Biological Process	GO:0009409	response to cold	ISO	J:155856