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GO Annotations Graph
Symbol
Name
ID
Prkcz
protein kinase C, zeta
MGI:97602

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:007188914-3-3 protein bindingISOJ:155856
Molecular FunctionGO:0005524ATP bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0043274phospholipase bindingISOJ:155856
Molecular FunctionGO:0015459potassium channel regulator activityISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:105811
Molecular FunctionGO:0005515protein bindingIPIJ:225409
Molecular FunctionGO:0005515protein bindingIPIJ:225407
Molecular FunctionGO:0005515protein bindingIPIJ:158132
Molecular FunctionGO:0005515protein bindingIPIJ:170429
Molecular FunctionGO:0019904protein domain specific bindingISOJ:155856
Molecular FunctionGO:0004672protein kinase activityIDAJ:87887
Molecular FunctionGO:0004672protein kinase activityISOJ:164563
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0004697protein kinase C activityISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:170429
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0045179apical cortexIDAJ:99397
Cellular ComponentGO:0016324apical plasma membraneIDAJ:161201
Cellular ComponentGO:0043203axon hillockIDAJ:158132
Cellular ComponentGO:0005923bicellular tight junctionIDAJ:99397
Cellular ComponentGO:0005923bicellular tight junctionIDAJ:97223
Cellular ComponentGO:0005938cell cortexIDAJ:99397
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0031252cell leading edgeISOJ:155856
Cellular ComponentGO:0005911cell-cell junctionISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:84405
Cellular ComponentGO:0005737cytoplasmIDAJ:87887
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:63657
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005768endosomeIEAJ:60000
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0031941colocalizes_with
filamentous actin
ISOJ:155856
Cellular ComponentGO:0043231intracellular membrane-bounded organelleISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0005815microtubule organizing centerIGIJ:158132
Cellular ComponentGO:0035748myelin sheath abaxonal regionIDAJ:159103
Cellular ComponentGO:0005635nuclear envelopeIDAJ:63657
Cellular ComponentGO:0016363nuclear matrixIDAJ:63657
Cellular ComponentGO:0005634nucleusIDAJ:63657
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneIDAJ:63657
Cellular ComponentGO:0043234protein complexIDAJ:105811
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0031982vesicleISOJ:164563
Cellular ComponentGO:0031982vesicleIDAJ:225407
Biological ProcessGO:0031532actin cytoskeleton reorganizationISOJ:155856
Biological ProcessGO:0031584activation of phospholipase D activityISOJ:155856
Biological ProcessGO:0032148activation of protein kinase B activityISOJ:155856
Biological ProcessGO:0016477cell migrationISOJ:155856
Biological ProcessGO:0007166cell surface receptor signaling pathwayISOJ:155856
Biological ProcessGO:0034613cellular protein localizationISOJ:155856
Biological ProcessGO:0032869cellular response to insulin stimulusISOJ:155856
Biological ProcessGO:0030010establishment of cell polarityISOJ:155856
Biological ProcessGO:0006954inflammatory responseIEAJ:60000
Biological ProcessGO:0008286insulin receptor signaling pathwayISOJ:155856
Biological ProcessGO:0035556intracellular signal transductionIBAJ:161428
Biological ProcessGO:0035556intracellular signal transductionISOJ:155856
Biological ProcessGO:0007616long-term memoryISOJ:155856
Biological ProcessGO:0060291long-term synaptic potentiationISOJ:155856
Biological ProcessGO:0051899membrane depolarizationISOJ:155856
Biological ProcessGO:0060081membrane hyperpolarizationISOJ:155856
Biological ProcessGO:0000226microtubule cytoskeleton organizationIGIJ:158132
Biological ProcessGO:0000226microtubule cytoskeleton organizationIMPJ:98926
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:155856
Biological ProcessGO:0051346negative regulation of hydrolase activityISOJ:155856
Biological ProcessGO:0046627negative regulation of insulin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0050732negative regulation of peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0031333negative regulation of protein complex assemblyISOJ:164563
Biological ProcessGO:1990138neuron projection extensionIGIJ:158132
Biological ProcessGO:0018105peptidyl-serine phosphorylationISOJ:155856
Biological ProcessGO:0018105peptidyl-serine phosphorylationIBAJ:161428
Biological ProcessGO:0018105peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:155856
Biological ProcessGO:0001954positive regulation of cell-matrix adhesionISOJ:155856
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:155856
Biological ProcessGO:2000463positive regulation of excitatory postsynaptic potentialISOJ:155856
Biological ProcessGO:0046326positive regulation of glucose importISOJ:155856
Biological ProcessGO:0046628positive regulation of insulin receptor signaling pathwayISOJ:155856
Biological ProcessGO:2001181positive regulation of interleukin-10 secretionIMPJ:99860
Biological ProcessGO:2000667positive regulation of interleukin-13 secretionIMPJ:99860
Biological ProcessGO:0032753positive regulation of interleukin-4 productionIMPJ:99860
Biological ProcessGO:2000664positive regulation of interleukin-5 secretionIMPJ:99860
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityISOJ:155856
Biological ProcessGO:0051222positive regulation of protein transportISOJ:155856
Biological ProcessGO:0050806positive regulation of synaptic transmissionISOJ:155856
Biological ProcessGO:2000553positive regulation of T-helper 2 cell cytokine productionIMPJ:99860
Biological ProcessGO:0045630positive regulation of T-helper 2 cell differentiationIMPJ:99860
Biological ProcessGO:0051291protein heterooligomerizationISOJ:155856
Biological ProcessGO:0070528protein kinase C signalingISOJ:155856
Biological ProcessGO:0072659protein localization to plasma membraneIMPJ:107908
Biological ProcessGO:0006468protein phosphorylationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationIDAJ:87887
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0007165signal transductionISOJ:155856
Biological ProcessGO:0047496vesicle transport along microtubuleISOJ:155856


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory