Pfn2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Pfn2
profilin 2
MGI:97550

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0003779	actin binding	IBA	J:265628
Molecular Function	GO:0003785	actin monomer binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:205619
Molecular Function	GO:0005515	protein binding	IPI	J:107428
Molecular Function	GO:0005515	protein binding	IPI	J:74533
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5665656
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:231072
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:122603
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:122603
Cellular Component	GO:0098794	postsynapse	IDA	J:122603
Cellular Component	GO:0098794	postsynapse	IDA	J:122603
Cellular Component	GO:0098793	presynapse	IDA	J:122603
Cellular Component	GO:0098793	presynapse	IDA	J:122603
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:122603
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:122603
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:122603
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:122603
Biological Process	GO:0030036	actin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	IDA	J:231072
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	IDA	J:231072
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	IDA	J:231072
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	IDA	J:231072
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	IMP	J:231072
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:231072
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:231072
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:231072
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:231072
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:231072
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0010633	negative regulation of epithelial cell migration	ISO	J:164563
Biological Process	GO:0010633	negative regulation of epithelial cell migration	IMP	J:205619
Biological Process	GO:1900028	negative regulation of ruffle assembly	ISO	J:164563
Biological Process	GO:1900028	negative regulation of ruffle assembly	IMP	J:205619
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	IBA	J:265628
Biological Process	GO:0030838	positive regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0030838	positive regulation of actin filament polymerization	IMP	J:122603
Biological Process	GO:0032781	positive regulation of ATP-dependent activity	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IMP	J:205619
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0051496	positive regulation of stress fiber assembly	IMP	J:205619
Biological Process	GO:0051496	positive regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IDA	J:122603
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	IMP	J:122603
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	ISO	J:155856
Biological Process	GO:0030833	regulation of actin filament polymerization	IBA	J:265628
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:122603

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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