GO Annotations Graph

• Symbol: P4hb
• Name: prolyl 4-hydroxylase, beta polypeptide
• ID: MGI:97464

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	IPI	J:173540
Molecular Function	GO:0016853	isomerase activity	IEA	J:60000
Molecular Function	GO:0004656	procollagen-proline 4-dioxygenase activity	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:313853
Molecular Function	GO:0005515	protein binding	IPI	J:173540
Molecular Function	GO:0003756	protein disulfide isomerase activity	ISO	J:155856
Molecular Function	GO:0003756	protein disulfide isomerase activity	ISO	J:164563
Molecular Function	GO:0003756	protein disulfide isomerase activity	IBA	J:265628
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0015035	protein-disulfide reductase activity	ISO	J:164563
Molecular Function	GO:0015035	protein-disulfide reductase activity	IMP	J:276798
Molecular Function	GO:0016972	thiol oxidase activity	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:242513
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:109257
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:195351
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:51036
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:89660
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:97560
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:135444
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:158452
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:46305
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IDA	J:217288
Cellular Component	GO:0005788	endoplasmic reticulum lumen	IMP	J:276798
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:173540
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0016222	procollagen-proline 4-dioxygenase complex	ISO	J:73065
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0098761	cellular response to interleukin-7	IDA	J:260356
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IMP	J:276798
Biological Process	GO:0030070	insulin processing	IMP	J:276798
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	ISO	J:25202
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	ISO	J:164563
Biological Process	GO:0046598	positive regulation of viral entry into host cell	ISO	J:164563
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0034975	protein folding in endoplasmic reticulum	ISO	J:164563
Biological Process	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IBA	J:265628