GO Annotations Graph

• Symbol: Mt1
• Name: metallothionein 1
• ID: MGI:97171

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005507	copper ion binding	IDA	J:43685
Molecular Function	GO:0046872	metal ion binding	IDA	J:79346
Molecular Function	GO:0046872	metal ion binding	IDA	J:90733
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	TAS	J:75601
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6798570
Cellular Component	GO:0005829	cytosol	IDA	J:43685
Cellular Component	GO:0005764	lysosome	IDA	J:43685
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0071247	cellular response to chromate	IDA	J:142329
Biological Process	GO:0071280	cellular response to copper ion	IBA	J:265628
Biological Process	GO:0071294	cellular response to zinc ion	IDA	J:142329
Biological Process	GO:0010273	detoxification of copper ion	IGI	J:33276
Biological Process	GO:0010273	detoxification of copper ion	IGI	J:33276
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	IDA	J:79346
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	IDA	J:90733
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:75601
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:182374
Biological Process	GO:0007263	nitric oxide mediated signal transduction	IMP	J:75601