Marcks GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Marcks
myristoylated alanine rich protein kinase C substrate
MGI:96907

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	IPI	J:240291
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005516	calmodulin binding	IPI	J:240291
Molecular Function	GO:0042802	identical protein binding	IDA	J:240291
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	ISO	J:155856
Molecular Function	GO:0005080	protein kinase C binding	IPI	J:51810
Cellular Component	GO:0032432	actin filament bundle	IDA	J:240291
Cellular Component	GO:0032432	actin filament bundle	IBA	J:265628
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0032059	bleb	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	IDA	J:98298
Cellular Component	GO:0005938	cell cortex	IDA	J:98298
Cellular Component	GO:0005813	centrosome	IDA	J:98298
Cellular Component	GO:0033391	chromatoid body	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:98298
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0044307	dendritic branch	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0042585	germinal vesicle	IDA	J:98298
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:85090
Cellular Component	GO:0005874	microtubule	ISO	J:155856
Cellular Component	GO:0043226	organelle	IDA	J:270211
Cellular Component	GO:0001520	outer dense fiber	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0099571	postsynaptic cytoskeleton	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099523	presynaptic cytosol	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0051764	actin crosslink formation	IDA	J:240291
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:240291
Biological Process	GO:0007015	actin filament organization	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0031584	activation of phospholipase D activity	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IMP	J:270211
Biological Process	GO:0031589	cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	ISO	J:155856
Biological Process	GO:0007005	mitochondrion organization	IDA	J:270211
Biological Process	GO:0021915	neural tube development	IMP	J:270211
Biological Process	GO:0022008	neurogenesis	IMP	J:270211
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	ISO	J:155856
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1900020	positive regulation of protein kinase C activity	ISO	J:155856
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	ISO	J:155856
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IDA	J:270211

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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