GO Annotations Graph

• Symbol: L1cam
• Name: L1 cell adhesion molecule
• ID: MGI:96721

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IDA	J:125138
Molecular Function	GO:0042802	identical protein binding	IDA	J:38402
Molecular Function	GO:0005178	integrin binding	IDA	J:125138
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:136695
Molecular Function	GO:0005515	protein binding	IPI	J:137627
Molecular Function	GO:0005515	protein binding	IPI	J:137627
Molecular Function	GO:0005515	protein binding	IPI	J:84104
Molecular Function	GO:0005515	protein binding	IPI	J:38402
Molecular Function	GO:0005515	protein binding	IPI	J:120470
Molecular Function	GO:0005515	protein binding	IPI	J:26606
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	IPI	J:137627
Molecular Function	GO:0033691	sialic acid binding	IDA	J:120470
Molecular Function	GO:0033691	sialic acid binding	IDA	J:158148
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0044295	axonal growth cone	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:88274
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0044294	dendritic growth cone	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:17350
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:26606
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:26606
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:106989
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:106989
Cellular Component	GO:0016020	membrane	IDA	J:120470
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-437240
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-443770
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-443785
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:106989
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:106989
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:106989
Cellular Component	GO:0043195	terminal bouton	IDA	J:106989
Biological Process	GO:0061564	axon development	ISO	J:164563
Biological Process	GO:0007411	axon guidance	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IGI	J:137627
Biological Process	GO:0007411	axon guidance	IGI	J:137627
Biological Process	GO:0007411	axon guidance	IMP	J:81739
Biological Process	GO:0007411	axon guidance	IMP	J:137627
Biological Process	GO:0007411	axon guidance	IDA	J:138244
Biological Process	GO:0007413	axonal fasciculation	ISO	J:155856
Biological Process	GO:0019722	calcium-mediated signaling	IDA	J:26606
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:26606
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	IMP	J:125138
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:125138
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IBA	J:265628
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IMP	J:125140
Biological Process	GO:0034109	homotypic cell-cell adhesion	IMP	J:26606
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:125144
Biological Process	GO:0007159	leukocyte cell-cell adhesion	IMP	J:125138
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	IMP	J:120470
Biological Process	GO:0031175	neuron projection development	IDA	J:120470
Biological Process	GO:0045773	positive regulation of axon extension	ISO	J:155856
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IDA	J:26606
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:125140
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0050808	synapse organization	ISO	J:164563
Biological Process	GO:0050808	synapse organization	IBA	J:265628