GO Annotations Graph

• Symbol: Krt2
• Name: keratin 2
• ID: MGI:96699

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	IMP	J:214772
Molecular Function	GO:0030280	structural constituent of skin epidermis	ISO	J:164563
Molecular Function	GO:0030280	structural constituent of skin epidermis	IBA	J:265628
Molecular Function	GO:0030280	structural constituent of skin epidermis	IMP	J:214772
Cellular Component	GO:0001533	cornified envelope	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:214772
Cellular Component	GO:0005882	intermediate filament	IEA	J:60000
Cellular Component	GO:0045095	keratin filament	IBA	J:265628
Cellular Component	GO:0045095	keratin filament	IDA	J:214772
Biological Process	GO:0008544	epidermis development	IMP	J:214772
Biological Process	GO:0008544	epidermis development	IMP	J:214772
Biological Process	GO:0045109	intermediate filament organization	IBA	J:265628
Biological Process	GO:0045109	intermediate filament organization	IMP	J:214772
Biological Process	GO:0045109	intermediate filament organization	IMP	J:214772
Biological Process	GO:0031424	keratinization	ISO	J:164563
Biological Process	GO:0031424	keratinization	IBA	J:265628
Biological Process	GO:0032980	keratinocyte activation	ISO	J:164563
Biological Process	GO:0003334	keratinocyte development	IMP	J:214772
Biological Process	GO:0003334	keratinocyte development	IMP	J:214772
Biological Process	GO:0051546	keratinocyte migration	ISO	J:164563
Biological Process	GO:0043616	keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0018149	peptide cross-linking	ISO	J:164563
Biological Process	GO:0045684	positive regulation of epidermis development	IMP	J:252645