Kcna1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
MGI:96654

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IDA	J:215654
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:226018
Molecular Function	GO:0005515	protein binding	IPI	J:230557
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:155856
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:215654
Molecular Function	GO:0005249	voltage-gated potassium channel activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:170639
Cellular Component	GO:0030424	axon	IDA	J:226018
Cellular Component	GO:0030424	axon	IDA	J:19538
Cellular Component	GO:0043194	axon initial segment	IDA	J:149503
Cellular Component	GO:0043679	axon terminus	IDA	J:170639
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IDA	J:19538
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:201521
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:19538
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0030425	dendrite	IDA	J:201521
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	ISO	J:164563
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:215893
Cellular Component	GO:0044224	juxtaparanode region of axon	ISO	J:155856
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:85502
Cellular Component	GO:0044224	juxtaparanode region of axon	IBA	J:265628
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0044224	juxtaparanode region of axon	IDA	J:142445
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:19538
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:201521
Cellular Component	GO:0033270	paranode region of axon	IDA	J:19538
Cellular Component	GO:0033270	paranode region of axon	ISO	J:155856
Cellular Component	GO:0033270	paranode region of axon	ISO	J:164563
Cellular Component	GO:0033270	paranode region of axon	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	IDA	J:226018
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IMP	J:215654
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0034705	potassium channel complex	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:19538
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:215893
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:164563
Cellular Component	GO:0008076	voltage-gated potassium channel complex	ISO	J:155856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IBA	J:265628
Biological Process	GO:0007420	brain development	IMP	J:178006
Biological Process	GO:0010644	cell communication by electrical coupling	ISO	J:155856
Biological Process	GO:0071286	cellular response to magnesium ion	IMP	J:217265
Biological Process	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	IMP	J:197938
Biological Process	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch	IMP	J:197938
Biological Process	GO:0021766	hippocampus development	IMP	J:217281
Biological Process	GO:0010960	magnesium ion homeostasis	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0007405	neuroblast proliferation	IMP	J:217281
Biological Process	GO:0050905	neuromuscular process	IMP	J:77281
Biological Process	GO:0050905	neuromuscular process	ISO	J:164563
Biological Process	GO:0019228	neuronal action potential	IMP	J:77281
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0023041	neuronal signal transduction	ISO	J:155856
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IDA	J:215654
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	IEA	J:72247
Biological Process	GO:0006813	potassium ion transport	IEA	J:60000
Biological Process	GO:0051260	protein homooligomerization	IEA	J:72247
Biological Process	GO:0008104	protein localization	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0006937	regulation of muscle contraction	ISO	J:155856
Biological Process	GO:0001964	startle response	IMP	J:178006
Biological Process	GO:0001964	startle response	ISO	J:155856
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23