GO Annotations Graph

• Symbol: Igha
• Name: immunoglobulin heavy constant alpha
• ID: MGI:96444

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003823	antigen binding	IDA	J:30239
Molecular Function	GO:0003823	antigen binding	IDA	J:31133
Molecular Function	GO:0003823	antigen binding	IDA	J:88910
Molecular Function	GO:0003823	antigen binding	IDA	J:107174
Molecular Function	GO:0034987	immunoglobulin receptor binding	ISO	J:164563
Molecular Function	GO:0034987	immunoglobulin receptor binding	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:107174
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:89322
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:19552
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:88910
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:30239
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:31133
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:65439
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:64281
Cellular Component	GO:0042571	immunoglobulin complex, circulating	IDA	J:85084
Cellular Component	GO:0071748	monomeric IgA immunoglobulin complex	ISO	J:164563
Cellular Component	GO:0071748	monomeric IgA immunoglobulin complex	ISO	J:164563
Cellular Component	GO:0071752	secretory dimeric IgA immunoglobulin complex	ISO	J:164563
Cellular Component	GO:0071752	secretory dimeric IgA immunoglobulin complex	ISO	J:164563
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	ISO	J:164563
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	ISO	J:164563
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	IDA	J:107174
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	IDA	J:88910
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	IDA	J:30239
Biological Process	GO:0016064	immunoglobulin mediated immune response	IDA	J:31133
Biological Process	GO:0002385	mucosal immune response	IDA	J:88910