GO Annotations Graph

• Symbol: Igf2r
• Name: insulin-like growth factor 2 receptor
• ID: MGI:96435

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005520	insulin-like growth factor binding	IBA	J:265628
Molecular Function	GO:0005520	insulin-like growth factor binding	IPI	J:86296
Molecular Function	GO:0031995	insulin-like growth factor II binding	ISO	J:155856
Molecular Function	GO:0005537	mannose binding	IDA	J:129362
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:129362
Molecular Function	GO:0001972	retinoic acid binding	ISO	J:155856
Molecular Function	GO:1905394	retromer complex binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	IEA	J:72247
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0030118	clathrin coat	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0030139	endocytic vesicle	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:89488
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0005770	late endosome	ISO	J:73065
Cellular Component	GO:0016020	membrane	IDA	J:129362
Cellular Component	GO:0016020	membrane	IDA	J:129362
Cellular Component	GO:0005641	nuclear envelope lumen	IDA	J:84286
Cellular Component	GO:0005634	nucleus	IDA	J:84286
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IBA	J:265628
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	ISO	J:89488
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0001889	liver development	ISO	J:155856
Biological Process	GO:0007041	lysosomal transport	IBA	J:265628
Biological Process	GO:0044794	positive regulation by host of viral process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0042981	regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0032526	response to retinoic acid	ISO	J:155856