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GO Annotations Graph
Symbol
Name
ID
Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
MGI:96414

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0004450isocitrate dehydrogenase (NADP+) activityISOJ:164563
Molecular FunctionGO:0004450isocitrate dehydrogenase (NADP+) activityISOJ:155856
Molecular FunctionGO:0004450isocitrate dehydrogenase (NADP+) activityIDAJ:135295
Molecular FunctionGO:0004450isocitrate dehydrogenase (NADP+) activityIDAJ:32977
Molecular FunctionGO:0004450isocitrate dehydrogenase (NADP+) activityIDAJ:6674
Molecular FunctionGO:0000287magnesium ion bindingIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0051287NAD bindingIEAJ:72247
Molecular FunctionGO:0016491oxidoreductase activityIEAJ:60000
Molecular FunctionGO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorIEAJ:72247
Cellular ComponentGO:0005829cytosolIDAJ:135295
Cellular ComponentGO:0005743mitochondrial inner membraneHDAJ:100953
Cellular ComponentGO:0005739mitochondrionISOJ:164563
Cellular ComponentGO:0005739mitochondrionIBAJ:265628
Cellular ComponentGO:0005739mitochondrionHDAJ:86816
Cellular ComponentGO:0005739mitochondrionHDAJ:86816
Cellular ComponentGO:0005739mitochondrionHDAJ:86816
Cellular ComponentGO:0005739mitochondrionHDAJ:86816
Cellular ComponentGO:0005739mitochondrionHDAJ:151002
Cellular ComponentGO:0005777peroxisomeIDAJ:135295
Biological ProcessGO:0006097glyoxylate cycleIEAJ:60000
Biological ProcessGO:0006102isocitrate metabolic processIEAJ:72247
Biological ProcessGO:0006741NADP biosynthetic processISOJ:155856
Biological ProcessGO:0006739NADP metabolic processIBAJ:265628
Biological ProcessGO:1903976negative regulation of glial cell migrationISOJ:155856
Biological ProcessGO:0060253negative regulation of glial cell proliferationISOJ:155856
Biological ProcessGO:1904465negative regulation of matrix metallopeptidase secretionISOJ:155856
Biological ProcessGO:0006099tricarboxylic acid cycleIEAJ:60000

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory