GO Annotations Graph

• Symbol: Htr3a
• Name: 5-hydroxytryptamine (serotonin) receptor 3A
• ID: MGI:96282

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	IPI	J:247405
Molecular Function	GO:0042802	identical protein binding	IPI	J:245295
Molecular Function	GO:0042802	identical protein binding	IPI	J:247387
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	NAS	J:326649
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA	J:326649
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IDA	J:326649
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	IMP	J:326649
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030594	neurotransmitter receptor activity	IBA	J:265628
Molecular Function	GO:0051378	serotonin binding	ISO	J:30225
Molecular Function	GO:0022850	serotonin-gated monoatomic cation-selective channel activity	ISO	J:155856
Molecular Function	GO:0022850	serotonin-gated monoatomic cation-selective channel activity	ISO	J:164563
Molecular Function	GO:0022850	serotonin-gated monoatomic cation-selective channel activity	ISO	J:30225
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:1904602	serotonin-activated cation-selective channel complex	IPI	J:245295
Cellular Component	GO:1904602	serotonin-activated cation-selective channel complex	ISO	J:164563
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0098662	inorganic cation transmembrane transport	ISO	J:164563
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IDA	J:326649
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0032414	positive regulation of ion transmembrane transporter activity	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0099505	regulation of presynaptic membrane potential	IDA	J:326649
Biological Process	GO:0007210	serotonin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IBA	J:265628