Hspg2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hspg2
perlecan (heparan sulfate proteoglycan 2)
MGI:96257

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0070052	collagen V binding	ISO	J:155856
Molecular Function	GO:0030021	extracellular matrix structural constituent conferring compression resistance	RCA	J:265607
Molecular Function	GO:0030021	extracellular matrix structural constituent conferring compression resistance	RCA	J:265604
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0002020	protease binding	IPI	J:206911
Molecular Function	GO:0005515	protein binding	IPI	J:206911
Molecular Function	GO:0005515	protein binding	IPI	J:79202
Molecular Function	GO:0005515	protein binding	IPI	J:110553
Cellular Component	GO:0005604	basement membrane	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:58700
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:81999
Cellular Component	GO:0005604	basement membrane	IDA	J:73993
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:98778
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:27732
Cellular Component	GO:0005604	basement membrane	IDA	J:55507
Cellular Component	GO:0005604	basement membrane	IDA	J:95191
Cellular Component	GO:0005604	basement membrane	IDA	J:74542
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0031012	extracellular matrix	IDA	J:95191
Cellular Component	GO:0031012	extracellular matrix	IDA	J:58700
Cellular Component	GO:0031012	extracellular matrix	IDA	J:110553
Cellular Component	GO:0031012	extracellular matrix	IDA	J:194150
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426528
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426638
Cellular Component	GO:0005796	Golgi lumen	TAS	Reactome:R-MMU-2024090
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0007420	brain development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0048738	cardiac muscle tissue development	IMP	J:58700
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	IMP	J:67299
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	IMP	J:67299
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:67299
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:67299
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:58700
Biological Process	GO:0001958	endochondral ossification	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:58700
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:155856
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0008104	protein localization	IMP	J:74542
Biological Process	GO:0006898	receptor-mediated endocytosis	IGI	J:241063
Biological Process	GO:0006898	receptor-mediated endocytosis	IMP	J:241063
Biological Process	GO:0006898	receptor-mediated endocytosis	IGI	J:241063
Biological Process	GO:0007224	smoothened signaling pathway	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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