GO Annotations Graph

• Symbol: Slc6a3
• Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
• ID: MGI:94862

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043176	amine binding	ISO	J:155856
Molecular Function	GO:0035240	dopamine binding	IDA	J:140050
Molecular Function	GO:0005330	dopamine:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0005330	dopamine:sodium symporter activity	IDA	J:56251
Molecular Function	GO:0005330	dopamine:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0005330	dopamine:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005330	dopamine:sodium symporter activity	IMP	J:79010
Molecular Function	GO:1901363	heterocyclic compound binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	IMP	J:289076
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	ISO	J:100021
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	IMP	J:289076
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0005334	norepinephrine:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0002020	protease binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:136786
Molecular Function	GO:0005515	protein binding	IPI	J:147424
Molecular Function	GO:0005515	protein binding	IPI	J:201939
Molecular Function	GO:0051721	protein phosphatase 2A binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0030424	axon	ISO	J:164563
Cellular Component	GO:0030424	axon	IDA	J:125222
Cellular Component	GO:0043679	axon terminus	IDA	J:136786
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:220508
Cellular Component	GO:0098691	dopaminergic synapse	ISO	J:155856
Cellular Component	GO:0016600	flotillin complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0032809	neuronal cell body membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IBA	J:265628
Biological Process	GO:0021984	adenohypophysis development	IMP	J:41856
Biological Process	GO:0021984	adenohypophysis development	IMP	J:41856
Biological Process	GO:0042416	dopamine biosynthetic process	IMP	J:79010
Biological Process	GO:0042420	dopamine catabolic process	IMP	J:79010
Biological Process	GO:0015872	dopamine transport	ISO	J:155856
Biological Process	GO:0015872	dopamine transport	ISO	J:164563
Biological Process	GO:0015872	dopamine transport	IMP	J:79010
Biological Process	GO:0090494	dopamine uptake	ISO	J:164563
Biological Process	GO:0090494	dopamine uptake	IMP	J:289076
Biological Process	GO:0051583	dopamine uptake involved in synaptic transmission	IBA	J:265628
Biological Process	GO:1990384	hyaloid vascular plexus regression	IDA	J:279052
Biological Process	GO:0007595	lactation	IMP	J:41856
Biological Process	GO:0007626	locomotory behavior	IMP	J:66955
Biological Process	GO:0007626	locomotory behavior	IGI	J:66955
Biological Process	GO:0007626	locomotory behavior	IGI	J:66955
Biological Process	GO:0015844	monoamine transport	ISO	J:100021
Biological Process	GO:0006836	neurotransmitter transport	IMP	J:289076
Biological Process	GO:0001504	neurotransmitter uptake	IMP	J:31328
Biological Process	GO:0001504	neurotransmitter uptake	IDA	J:31328
Biological Process	GO:0015874	norepinephrine transport	IBA	J:265628
Biological Process	GO:0040018	positive regulation of multicellular organism growth	IMP	J:41856
Biological Process	GO:0060134	prepulse inhibition	IMP	J:66955
Biological Process	GO:0042053	regulation of dopamine metabolic process	IMP	J:79010
Biological Process	GO:0042053	regulation of dopamine metabolic process	IMP	J:41856
Biological Process	GO:0051591	response to cAMP	ISO	J:155856
Biological Process	GO:0042220	response to cocaine	IDA	J:140050
Biological Process	GO:0045471	response to ethanol	ISO	J:155856
Biological Process	GO:0007608	sensory perception of smell	IMP	J:110704
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628