GO Annotations Graph

• Symbol: Cdh3
• Name: cadherin 3
• ID: MGI:88356

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045296	cadherin binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005912	adherens junction	IDA	J:97223
Cellular Component	GO:0005912	adherens junction	IDA	J:101707
Cellular Component	GO:0016342	catenin complex	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:77502
Biological Process	GO:0034332	adherens junction organization	IBA	J:265628
Biological Process	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:91137
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	IBA	J:265628
Biological Process	GO:0007043	cell-cell junction assembly	IBA	J:265628
Biological Process	GO:0022405	hair cycle process	ISO	J:164563
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IEA	J:72247
Biological Process	GO:0031424	keratinization	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0051796	negative regulation of timing of catagen	ISO	J:164563
Biological Process	GO:0032912	negative regulation of transforming growth factor beta2 production	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0048023	positive regulation of melanin biosynthetic process	ISO	J:164563
Biological Process	GO:1902910	positive regulation of melanosome transport	ISO	J:164563
Biological Process	GO:0032773	positive regulation of tyrosinase activity	ISO	J:164563
Biological Process	GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0001895	retina homeostasis	ISO	J:164563